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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFP
All Species:
27.27
Human Site:
Y358
Identified Species:
75
UniProt:
P02771
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02771
NP_001125.1
609
68678
Y358
L
A
S
F
V
H
E
Y
S
R
R
H
P
Q
L
Chimpanzee
Pan troglodytes
Q28789
609
68723
Y358
L
A
S
F
V
H
E
Y
S
R
R
H
P
Q
L
Rhesus Macaque
Macaca mulatta
Q28522
600
67862
Y350
L
G
M
F
L
Y
E
Y
A
R
R
H
P
D
Y
Dog
Lupus familis
XP_855557
608
68588
Y358
L
G
T
F
L
Y
E
Y
S
R
R
H
P
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
P02772
605
67319
Y354
M
A
S
F
L
H
E
Y
S
R
T
H
P
N
L
Rat
Rattus norvegicus
P02773
611
68368
Y360
M
A
S
F
L
H
E
Y
S
R
N
H
P
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511450
602
69140
Y355
L
D
E
F
V
Y
E
Y
S
R
K
H
Q
K
V
Chicken
Gallus gallus
P19121
615
69900
Y362
M
A
E
F
V
Y
E
Y
S
R
R
H
P
E
F
Frog
Xenopus laevis
P14872
607
70364
V357
L
G
R
Y
L
H
A
V
S
R
K
H
Q
E
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
38.5
40.2
N.A.
65.3
64.8
N.A.
38.4
40.3
31.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
58.1
59.6
N.A.
79.1
78.2
N.A.
59.9
61.2
52.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
60
N.A.
73.3
73.3
N.A.
53.3
66.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
86.6
N.A.
86.6
86.6
N.A.
80
86.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
56
0
0
0
0
12
0
12
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
23
0
0
0
89
0
0
0
0
0
0
34
0
% E
% Phe:
0
0
0
89
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
56
0
0
0
0
0
100
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
23
0
0
12
0
% K
% Leu:
67
0
0
0
56
0
0
0
0
0
0
0
0
0
56
% L
% Met:
34
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
0
0
23
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
78
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
23
23
0
% Q
% Arg:
0
0
12
0
0
0
0
0
0
100
56
0
0
0
0
% R
% Ser:
0
0
45
0
0
0
0
0
89
0
0
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
0
45
0
0
12
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
45
0
89
0
0
0
0
0
0
23
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _